Virology Networks   Utrecht NL
Virology Networks	Decision support application for drug regimens for HIV-infected patients
Keywords: decision support, evidence-based healthcare, disease management, HIV.

Product information

RetroGram Decision support for drug regimens for HIV-infected patients RetroGram relates complex genomic information on HIV-1 resistance to the clinical suitability of anti-retroviral drugs. RetroGram generates a suitability ranking of all FDA approved drugs based on their expected clinical efficacy for an individual patient. A unique feature of RetroGram is that it includes the experience and opinions of experts in the algorithm to weigh the effect of specific genotypic changes. RetroGram is available both as a stand-alone Windows-based application and in a Web-enabled version. RetroGram's clinical utility was highlighted in a large multi-centre study in Spain. Investigators concluded in their study that "HIV-1 genotyping interpreted by a software package improves the virological outcome when it is added to the clinical information as a basis for decisions on changing anti-retroviral therapy" [C Tural et al. Clinical utility of HIV-1 genotyping and expert advice: the Havana Trial. AIDS. 2002; 16:209-218]. RetroGram is currently being used in more than ten international comparison studies of all available genotype interpretation systems.

	Contact details
Virology Networks	Wilco Keulen Virology Networks BV. Maliebaan 24-26 3581 CP Utrecht The Netherlands Phone: +31 (0)30 230 71 40 F: +31 (0)30 236 80 25 E: retrogramvironet.com