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Methods and tools for the development of computer-interpretable guidelines

Austria  Many-Headed Bridge
XML-based intermediate representation to support formalisation of clinical guidelines and protocols
keywords Knowledge representation, computer-interpretable guidelines, Intermediate representation
developed by Institute of Software Technology and Interactive Systems at the Vienna University of Technology
introduced 2005
status Syntax specification is available (as is the DELT/A (Document Exploration and Linking Tool) - see below.
support EU Protocure II project
in use  
tools

The Vienna University of Technology tool, DELT/A (Document Exploration and Linking Tool with Add-ons), allows links between the original guideline text, its representation in MHB syntax, and its representation in a guideline formalism to be maintained.

 bullet  Many-Headed Bridge
description

The Many-Headed Bridge (MHB) to guideline formalization is an XML-based syntax designed to support structured organisation of a guideline to enable it to be formalised in any representation.

The semantics of the MHB allows each piece of guideline information to be defined along eight dimensions:

  1. control flow
  2. data flow
  3. temporal aspects
  4. evidence
  5. background information
  6. patient-related aspects
  7. resources
  8. document structure.

references

A. Seyfang, S. Miksch, M. Marcos et al. Bridging the Gap between Informal and Formal Guideline Representations. In Proc. "17th European Conference on Artificial Intelligence", G. Brewka, S. Coradeschi, A. Perini, P. Traverso (Eds.); IOS Press, 141 (2006)pp. 447 - 451.

[]   [TUW]

" Clinical guidelines are important means to improve quality of health care while limiting cost and supporting the medical staff. They are written as free text with tables and figures. Transforming them into a formal, computer-processable representation is a difficult task requiring both computer scientist skills and medical knowledge. To bridge this gap, we designed an intermediate representation (or ontology) which serves as a mediator between the original text and different formal guideline representations. It is easier to use than the latter, structures the original prose and helps to spot missing information and contradictions. In this paper we describe the representation and a practical evaluation thereof through the modelling of a real-world clinical guideline. "

C. Polo-Conde, M. Marcos, A. Seyfang et al. Assessment of MHB: an intermediate language for the representation of medical guidelines. In: Proc. 10th Conference of the Spanish Association for Artificial Intelligence (CAEPIA-05), Vol. I , pages I-19--I-28, Oct 2005.

[]   [Protocure project]

" The goal of the study described in this research paper is the assessment of a recently developed intermediate representation language, called MHB (Many-Headed Bridge), as an intermediate step within the clinical guidelines formalisation process. We qualitatively assess (1) whether it makes easier the formalisation of the guideline and, (2) to which degree MHB covers written text guideline features. For the assessment, we apply a multi-step formalisation process. In this practical approach, we have based our work on the CBO evidence-based clinical guideline for the treatment of the breast carcinoma. "

A Seyfang, S Miksch, C Polo et al. MHB - A Many-Headed Bridge between Informal and Formal Guideline Representations. In Proc. 10th European Conference on Artificial Intelligence in Medicine (AIME-05), Jul 2005.

[]   [Protocure project]

" Clinical guidelines become more and more important as a means to improve the quality of care by supporting the medical staff. Modeling guidelines in a computer-processable form is a prerequisite for various computer applications, to improve the quality of guidelines and to support their application. However, transforming the original text into a formal guideline representation is a difficult task requiring both computer scientist skills and medical knowledge. To bridge this gap, we designed an intermediate representation named MHB. "

contact Andreas Seyfang
Institute of Software Technology and Interactive System
Vienna University of Technology
Vienna
Austria

E: seyfangatifs.tuwien.ac.at

links  bullet  Many-Headed Bridge  bullet  DELT/A (Document Exploration and Linking Tool) [OC]  bullet  Protocure II project
acknowledgements
Andreas Seyfang, Vienna University of Technology, Institute of Software Technology and Interactive Systems, Vienna, Austria
page history
Entry on OpenClinical: 21 March 2007
Last main update: 21 March 2007
Design - template v0.3: 25 June 2005.

 

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