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The applications accessible from this site are for demonstration purposes only. They have not been validated for clinical use and must not be used for real patient encounters.


Demonstrations of clinical applications
DXplain    USA
Diagnostic decision support system for general medicine

developed by clinical domains keywords
Laboratory of Computer Science, Massachusetts General Hospital, Harvard Medical School, 1987-1999. General medicine WWW, electronic medical textbook, medical reference system, diagnostic clinical decision support tool
status access demonstrator
In clinical practice

DXplain logo
Annotated set of screens illustrating DXplain functionality

description

DXplain can be used as an electronic medical textbook, a medical reference system and as a diagnostic clinical decision support tool.

As a decision support system, DXplain "uses a set of clinical findings (signs, symptoms, laboratory data) to produce a ranked list of diagnoses which might explain (or be associated with) the clinical manifestations. DXplain provides justification for why each of these diseases might be considered, suggests what further clinical information would be useful to collect for each disease, and lists what clinical manifestations, if any, would be unusual or atypical for each of the specific diseases. " [Harvard Medical School]

DXplain is in routine use at a number of hospitals and medical schools for clinical education and as an educational aid in clinical problem solving. DXplain is owned by Massachusetts General Hospital and access is provided only after executing a license with MGH. DXplain is available as a web based application over the Internet. Access is limited to hospitals, medical schools, and health care institutions. Individual physicians and nurse practitioners may access DXplain over an Internet site maintained by MerckMedicus. Licensing information and an annotated demostration of DXplain are available at the Mass. General Hospital website.
references
Barnett GO, Famiglietti KT, Kim RJ, Hoffer EP, Feldman MJ. DXplain on the Internet. Proc AMIA Symp 1998;:607-11.

[PubMed]   []

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Elhanan G, Socratous SA, Cimino JJ. Integrating DXplain into a clinical information system using the World Wide Web. Proc AMIA Annu Fall Symp. 1996;:348-52.

[PubMed]   []

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Barnett GO, Hoffer EP, Packer MS, DXplain-demonstration and discussion of a diagnostic decision support system. Proc Annu Symp Comput Appl Med Care. 1992;:822.

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Feldman MJ, Barnett GO. An approach to evaluating the accuracy of DXplain. Comput Methods Programs Biomed. 1991 Aug;35(4):261-6.

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Barnett GO, Cimino JJ, Hupp JA, Hoffer EP. DXplain. An evolving diagnostic decision-support system. JAMA. 1987 Jul 3;258(1):67-74.

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contact links
Octo Barnett, MD, Laboratory of Computer Science, Massachusetts General Hospital, Harvard Medical School, Mass. USA.  bullet  Laboratory of Computer Science, Massachusetts General Hospital, Harvard Medical School
Acknowledgement
Octo Barnett, MD, Laboratory of Computer Science at Massachusetts General Hospital
Entry on OpenClinical: 11 July 2001
Last main update: 19 November 2001
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