AI systems in clinical practice

Laboratory systems
Coulter® FACULTY™
Expert System in clinical toxicology

developed by clinical domains keywords
Clinical toxicology, laboratory haematology Expert systems, Knowledge-Based Systems, workflow, educational tool
location commissioned status
The system was installed in 5 European hospitals: (1) St. Bartholomew's Hospital, London, UK; (2) Hospital Clinico, Valencia, Spain; (3) Hospital La Paz, Madrid, Spain; (4) St. Antonio's Hospital, Porto, Portugal; and (5) Cliniques Universitaires Mont-Godinne, Yvoir, Belgium. In addition, a Coulter symposium was held in conjunction with the British Society of Haematology meeting at the world-wide introduction of Coulter FACULTY and attendees (from the UK and the Netherlands) received the stand-alone educational version of the system. The five installations described above took place between October, 1995 and April 1996. Coulter FACULTY™ was released as a stand-alone product on April 26, 1996.
description
Coulter FACULTY™ Knowledge-Based System Software functions as a consultant, assists workflow, and acts as an educational tool in laboratory haematology.

FACULTY is available on CD-ROM. The package consists of:
(i) Two KBS modules, Professor Petrushka for peripheral blood interpretation, and Professor Fidelio for flow cytometry immunophenotyping and DNA content analysis;
(ii) A complete electronic textbook of peripheral blood interpretation with over 240 photomicrographs (Diagnostic Hematology: A Pattern Approach, Volume 1) which serves as the explanation facility for Professor Petrushka;
(iii) Database and printing utilities; and
(iv) Eight case studies, in a hypertext format identical to that used for the textbook, featuring Professor Petrushka, Professor Fidelio, and the next module to be released, Professor Belmonte for bone marrow interpretation. The system runs under the Windows (TM) operating system and requires a video card/monitor with a resolution of 800 x 600 x 64K colors. An interface to Coulter STKS 2B instruments is available from Coulter Corporation.

Three different interfaces are in use at user sites:

(1) At St. Bartholomew's, FACULTY™ is running on a five computer network with a bi-directional interface to the laboratory's LIS using a custom Coulter haematology communications server (HCS). Specimen orders are passed from the LIS to the HCS. The HCS filters the haematology specimens as they are run on a STKS. Normal specimens are routed directly to the LIS. Abnormal specimens artion, to the PGP system which downloads STKS data to the LIS. Abnormal specimens are stored in Professor Petrushka's database. Peripheral blood film review is performed using Professor Petrushka and the results are passed back to the LIS. Flow cytometry immunophenotyping results are stored in Professor Fidelio's database. We are currently setting up Professor Belmonte to process bone marrow reports;

(2) At the three sites in Spain and Portugal, FACULTY™ is installed on the IZASA-Coulter CITOTECA (R) Workstation which includes a mini-LIS (Modulab Plus), instrument interfaces, and a facility for capturing images from a video camera/microscope attached to the workstation. The FACULTY™ Paradox databases are interfaced to the dBase tables maintained by Modulab Plus;

(3) At Cliniques Universitares Mont-Godinne, FACULTY™ is interfaced, via a network connection, to the PGP system which downloads STKS data to the LIS.

references

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contact links

Dr. Lawrence W. Diamond and Dr. Doyen T. Nguyen, at Department of Haematology, St. Bartholomew's Hospital, London.

acknowledgements

Archive of AI systems in clinical practice previously administered by Enrico Coiera. Used with permission. Maintained and extended since 2001 by OpenClinical.

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